SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e7ca0c92320136a445df59aa30f355b6d2565cdfa5f035a72b3726bc280f16' 
  AND token = 'KJ6e9RFzuYuSnA1S8mvItUR9DdkeRk7gDof0QLmm7Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}