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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7200588f574c342f1b8fd9cb3a4ac4377d9116ac2bef237be2dd8d81ab40a947' 
  AND token = '50X6b1B5kpZeOMiSdcieISWjH3J3zVyrWSdnnQbfZ2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}