SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd275bc1717735703235d1dad97675b6eeb0626283e7f284cfaec429ffe2d32f' 
  AND token = 'xo649Kfq4kPl7YQ79CnXiSW6iMpYhzL5Qa9I8iSyrVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}