SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7317a16bd0cb414dfe863e3de0fd2b32e516f864235b2fca5dfbb2ac7606b95' 
  AND token = 'E3VUUIzhg0oRupYDJjknE/q4iHombqrA8nmrZmWmd74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}