SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec7ac8a05a6bfc0a15908792cbbca6a81b64400734288ccbcc75dcc873baf29' 
  AND token = 'hpR5T/vDubPznhXBA08qwNq6eSZNrmLWEl5wSY+Xa88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}