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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c7889979541a6b85a83885e1a8f7ee332ac44de6a9a94326f222864be8a0725' 
  AND token = '4mm6jnO84PbdpuIdotfEP/GM2hrVaeAlT1dKlDEsoJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}