SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022113cf4d66c65692dcfb33aa1650c0a31cba6b88ec2b4c1b3ba93f53226417' 
  AND token = 'YO8ICntmwzjgwpNV7AYEl4X/gvt/U15ScgFFh4ZFAoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}