SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d6f4ac7fc7aaf99e66d23e19278638f1eaef6bb5734dfc2f1d975dcc33edb1' 
  AND token = 'd3YCn/CncW73uTfyF1EbBgNzQaekf0xc+nI1k5OZWAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}