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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b43c84a510e92e92b73b623c394e198979d3078ba541476844b3c88c255a0213' 
  AND token = 'xa+FtY0LzpLgEWGAPbDbaB6QsJ0DnF2O0EB35HBL1Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}