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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca01a413fa05cd8b7f7a6d913fdd4b21723f199533055fc0d8b2aa5dbd7a247d' 
  AND token = 'muYouV0h7ls4GSfMZtLfLTE4rCLWhw+57hLg4OexiYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}