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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aea3ecf3cb2f77194d85daf3da1efdd35244992a6e589e7d5a7d83d7d0bf608c' 
  AND token = 'VNf1z2Jr3khEi6esMgT/vDkWWAyHzqzzsUjCMxzfKfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}