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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1821db2652b5b4e189de393d814afd3e87ee809b0f1a96e53f1d54bd4eae24d3' 
  AND token = 'zcPbIEgtM2TXfgibJKuswzDDFKejSYYU6/Bgb6A1DrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}