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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc264e8265e7040a4cf4d8afbcaefcbc05f6d8afa579054c9a129fe820db8d14' 
  AND token = 'Lz7caUE4L+oM1CUdbDMvCftCAETyhbRpTfCxa6vz8+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}