SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51973485a4c2ec2b293aec9853dfbd60eeba6943dc02316a674b7dc05045efb' 
  AND token = 'mNxDMK1bFciewAht3xJtdmy2bbjUAWHZ9GTilYI1PkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}