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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69c5ecaf7783292dceb944727124a9fa6c4f8134ed16c2f8c12cc273edc7fee1' 
  AND token = 'JVSNl7FzGFJy+yArlCGsB38Mf+J2vMX9GwS69UDC1xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}