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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d437ec308880ef3876b60ee32c6438edcbbf2ee776c3b5df65427e3d283f613' 
  AND token = 'y5oMA/HbgYFV107m1ftq+F5KNLBy9nfFv1bHV0Exw10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}