SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efe3fa781e860a443173e939a5166ba69c97614ef0cbe496a7125d03790b78fa' 
  AND token = 'g3E7NR0YKkl6dlM2UQgq4zm34tRhdD+jRySqvvMLyBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}