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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58bb794fffb6f2eface0ade38b8a567f11a16aeaed8978e1356dd09a0746fd1e' 
  AND token = 'xX32I4f+PIAjbDeg39L3WNy9sUPwFpNCYfP7kndd79M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}