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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bb48bb01f08bc29380a0c39f5d44e010fdbbbbc823e7497e54ae381d2c6bb22' 
  AND token = 'MK2uEewo9jXgAQ1tIwE1wiyEvVfwYdc4LUL9JL4w65U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}