SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f6b27b85817bd761cee891246cb1834382c1ff131022de6e16e5a1c4b840a56' 
  AND token = 'Ibq/gGRM2oCpj/VKfVNcKFyQLN3bv1UgGrnL7/rwD1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}