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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edee11a8c96b6d4cc831c1200a9c551fca63531447c7be2f767c3fa13d5ea441' 
  AND token = '4RwaUIDOG9PGh7EvOynlZbBhLo/4SE9KiVAzscUCNoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}