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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f005488565eb4c78731dd7825364b1d79e456af9ea38981759dd44421860d975' 
  AND token = 'isEEQ+21+zWwIHXgXM7Ote63iTCcPd+p/hgMJ7//GtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}