SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f2cec709ed4d78e9e110d8b5507129f185818c90a79b49c78b3479fc7724310' 
  AND token = 'OUg9NyeQhgZ/hUmC2cembutwYcTzzRh8yooFJCjtgcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}