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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6922cd53bb143cf07db7ce1dfd1b566069adac8be667e600504b1c9a2483eac1' 
  AND token = 'B1cJiNhCQqR5vGwoo9xhCSzw+JuPULn4a3d1zjA3waw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}