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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a041ba3a3147ec10a3dd75be0b77a7f2fc2e36edec2979c1f14d9e9949fd167' 
  AND token = 'SWCn+FWUF/Cm2h4g/1/Fb7xi+90j86lC3FvahY33AtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}