SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4648ca7eafc7fb0170284c2d8d405c9d89e8f0948378a36e2d7683f6fa0ec7aa' 
  AND token = '0eA53uuczc2NKy2R/lW5/Dc85H4V/Z/amlo4agTDKxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}