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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47221156cc750a4d2ffe41222c1d96b2fd54e63596ccdc0e51946c5fe5a772d0' 
  AND token = 'R1pMsK/R79D0gSfUyeOHeuLdwP1fsvJlxsLQom389ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}