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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd3c9ee1b7ee23474b43669a33dd99bcabade7073034be3614b7538aba6d1c7' 
  AND token = 'HWpkcEguVuuuG2+fPtaYb2mxulS3wsgwU4Y1jp7IDrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}