SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d9f1141ae0774b5704724356b6cf2f52cce2c896e8e725179cd130d799e032' 
  AND token = 'VCIlrL/TvVzRcxSUjl4uPRHzSS3X7le8Vn16MfIFoMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}