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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4d2f44f9a4c5ecd44f76178e4e7ec06881d933b7d31a28b7993e4cce4c007a' 
  AND token = 'N8rVsjVd5txuiaDw2iiaZfn8WzbEwSB7Z6iblV5FKkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}