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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd04ac010fe196f0b3c38cf3965f7b67aeb74ca527160c50f247aa2755dff5769' 
  AND token = 'J0+564k+O1aTGGGY5SJdthZYOchJcoDCSPCpSrLjLFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}