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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2f14d9e411b2622afc704f4af305e0c14469b1a6705d8c264227be4c5e55614' 
  AND token = 'v/48eHGhVdZ3SYpECiW/StHZQ5wdoiq9+uxGT4dHT3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}