SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e596c2b5fc198b742a74b59203bb05980f862a90c528bbabdb3dee3e4c73f09' 
  AND token = 'agY5wppnh4O3GsRtpZ/j7yi/vGHcy+3nYfNtzE0m+j4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}