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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '362b03cb0eafe45a2b125106b798dbd61102d628ba44887ee595b3b557844b73' 
  AND token = 'tzPvqaYfbbsTwYPjrptbAb/i6WDZHD1m3WLXWcqWzhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}