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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0f178bcf793dfab883f569e775736fdd5967ffa7c2f3e2c0739d3315a574cbd' 
  AND token = '1nQJh35s+3DQtv0zhP5KoYbAQtHil8FEhpUApBQpTBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}