SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a367e0a7db80b5cc15b0822d21d76cfdc912a377776fe803f3d6b9ede10c6f2' 
  AND token = 'SFaUMVcu5lSmLxl2OmdmcHie4+aGsWNg6/c2Yzemp5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}