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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c861000c99bd8b75b575f9c62a18220949a67820b5607c0b58022c75d826e5' 
  AND token = '/wQtrR+xzXFDJ/B8BGDyOE/RjFMtneIa+BatcHzgTwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}