SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a94ccfae6bf9b8f1a8dbb225c43834d10bddeeda60131768aeba93c5bc581d7' 
  AND token = 'b2V9LYyPKhxZfVxupPfwxSIVPKEsNcKBvHCwuvlpm/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}