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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225e86c9c57849aa42b2c92d52b845cc974de5998a17a075e7ef1c4459178583' 
  AND token = 'Qv71evC+nnDpplzF+xShfwkpaMwigWkfIOSNva29zVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}