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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3d2ce4b700fef98fb5c8026cab808f17e2c7bd8654a3426ba04fc2a2bec582' 
  AND token = 'AGA86wow8535vRtarPj8oAnwfyRz47RLHZGBDQmTt28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}