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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81fb1d17fbeeb447d13d061d431bb0fd6e072e0160b7848549c87980ede55d55' 
  AND token = 'BriwEa7H/w7Ax+cA5retKcTmKxyeRFLOpg23sd7sBZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}