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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d224e9687d7f0cf65c9f649bc2e886c19a0fefc17c1d5b7bf4e927f6f4f40a4' 
  AND token = 'bJgGmydz7rDX0gzlw9vEUhQKMSsbsc6ZBiu4WBq2pU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}