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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17a51a18ae009a40e5903f14d3f8f1a37825fe755f8cb23ae8288295733bc192' 
  AND token = '8iRsM2+f6nlCLJ2pyJG6Myz+CKJjw0BTie9v3rqTRPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}