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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f8b75fbab015e277c4334a9ce495a6484695801493cd1912dbeca899624bdb2' 
  AND token = 'UTGhbij8sRe3Cbl3chkhQAr9zgFyVSes8T9efs54pyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}