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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecad22b2142b650fdc0a8a13b3b632556b899c8b59f211657934891b783e790f' 
  AND token = 'v8b7PBPTjky7mWUEg16F6MdUTicQIXhqULDgNcuuBcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}