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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fccfe810db57db881e76dd2020a23b4b133fd495ea39368bc0d8118ad58cee96' 
  AND token = 'kaCkMWwstKR6t0LCHOtI4MtMzPdhZdNXKzD75EoqVlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}