SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f27920eba649fe5a453726443b2c046a00f9c15622c16211d0ab0fab903a1b' 
  AND token = 'JlB8g115aWG59S8R+ABgkIpLpdBcVosz8uzviFkansI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}