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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1940a492c4ec08025a428959c2b02ad394c036250e37040eb745b8396b4157' 
  AND token = 'fSfql+R5Hbt20/pzRZ1uBzKXxXPBeG2LPMkQfmWxCnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}