SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443ea65b0138364e49a85a519fd4348289f6917cb4bb7abba20f420d433ef74d' 
  AND token = '1TCNR6ilbN2vRP2PusGf6pqw3rxcCM8RSM+88C8Reak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}