SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff147398eeddc2530956980321d5fa8db1518e9b01b41c3663a919f4373f401' 
  AND token = 'nyRouf2aWtGC2U/bMnnCBAHHDDqjuuAj45uxLvy0LF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}